The Important Interaction Between Anandamide & Cannabinoids
The Important Interaction Between Anandamide & Cannabinoids
Health

How Anandamide Affects The Highs & Lows Of Your Cannabis Experience

The Important Interaction Between Anandamide & Cannabinoids
Health

How Anandamide Affects The Highs & Lows Of Your Cannabis Experience

Author Contributing Writer
PUBLISHED
Aug 08, 2021
read time 3 MIN
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The body is filled with intricate systems that allow our body and mind to connect. The use of cannabis, whether packed in a pre-rolled cone or a vaporizer, has different effects on individuals. Sativa and Indica strains have their own unique properties that affect our bodies differently through varying THC and CBD levels. Both cannabinoids are the most notable, largely because of the medicinal values they yield. The endocannabinoid system is responsible for how your body reacts to cannabis and it’s broken down into different molecules that play significant roles in our day-to-day functions.

The endocannabinoid system does interact with cannabis but there’s more to its job than helping you manage your high. The ECS is broken down into three different parts: endocannabinoids, receptors in your body and nervous system to bond endocannabinoids and cannabinoids, and enzymes that help the body break them down. Simply put, endocannabinoids are naturally occurring chemicals in your body with similarities to cannabinoids found in marijuana. Cannabinoids in plants are called phytocannabinoids, while cannabinoids in animals are called endocannabinoids.

To put it in focus, Anandamide is a particular endocannabinoid in the body that connects to both CB1 and CB2 receptors. It takes its name from a word in Sanskrit that translates to bliss. Suffice to say, anandamide is particularly effective on your level of happiness, even in small doses.

Can Anandamide Make You High?

No. Anandamide occurs in the ECS naturally with powerful effects. Though it is necessary for experiencing feelings of bliss, as the name suggests, the release of anandamide in your body is necessary for balance. In fact, there are studies that suggest an overabundance of the molecule overstimulates CB1 receptors and leads to negative effects.

Anandamide can’t be brought to a liquid state. It’s an endocannabinoid that requires fatty acid amide hydrolase and Monoacylglycerol lipas to be broken down, or even allow Anandamide to be present in the body. 

CBD, THC, & Anandamides

Anandamide does have important yet contrasting effects with both THC and CBD, the two most common cannabinoids.

The endocannabinoid system produces Anandamide but the cannabinoid system is responsible for creating phytocannabinoids. There are at least 113 phytocannabinoids, including THC and CBD, that all interact with the ECS differently.

As previously mentioned, Anandamide is responsible for experiencing elation so the psychoactive components of THC go hand-in-hand. THC attempts to recreate Anandamide in the body which plays a massive role in how it binds to CB1 and CB2 receptors. Thus, the feeling of happiness when you’re stoned.

CBD, on the other hand, doesn’t pair to the CB1 or CB2 receptors in the endocannabinoid system. Instead, it influences the ECS to create its own endocannabinoids, essentially boosting natural production. What CBD does is produce fatty acid amide hydrolase and Monoacylglycerol lipas which, as previously mentioned, breaks down Anandamide. In doing so, the Anandamide that’s available to the receptors magnifies. It explains the essence of CBD’s medicinal values without producing any sort of actual “high.”

Boosting Anandamide

While consuming cannabis, whether THC or CBD products, does have important interactions with Anandamide, it doesn’t help boost it within your system. However, there are a few ways to make sure that happens, whether through the foods you eat or your everyday activities. Medical professionals have previously suggested that things like physical activity can have a significant boost on your endocannabinoid system. A half an hour of exercise is said to produce a rise in Anandamide.

While overconsumption of anything does no good, there is something to be said about the benefits of chocolate. Dark chocolate, specifically, is said to help blood flow, improve brain function and reduce the risk of heart disease. Turns out, pure cacao also has the ability to boost anandamide.

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